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DeCS
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Descriptor English:
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Drug Tolerance
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Descriptor Spanish:
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tolerancia a medicamentos
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Descriptor Portuguese:
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Tolerāncia a Medicamentos
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Synonyms English:
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Drug Tolerances
Tolerance, Drug
Tolerances, Drug
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Tree Number:
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G07.690.773.992
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Definition English:
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Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL. |
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Indexing Annotation English:
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differentiate from DRUG RESISTANCE; not for tolerability ( = drug /adv eff): Manual 28.19
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Allowable Qualifiers English:
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Record Number:
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4420
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Unique Identifier:
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D004361
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Occurrence in VHL:
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Similar:
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DeCS
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